Preparation of a medicine form containing amorphous empagliflozin by means of hot-melt extrusion

摘要

the solution describes the method of preparation empagliflozinu in amorphous form by hot melt extrusion.the resulting empagliflozin is either in the form of amorphous dispersions in a pharmaceutically acceptable polymeror in the form of a solid solution with the pharmaceutically acceptable polymer, and can be used for the treatment or prevention of type 2 diabetes.part of the solution is also a pharmaceutical compositions containing empagliflozin prepared by hot melt extrusion.