;Described are deuterated catecholamine derivatives prepared by mixing compounds of the general Formula (II) wherein R4 is hydrogen, deuterium, C1-C6alkyl or C5-C6cycloalkyl, deuterated C1-C6alkyl or deuterated C5-C6cycloalkyl. The compounds can easily be prepared by mixing deuterated and non-deuterated compounds in a predefined ratio. The compounds show anti-Parkinson effect at lower doses and show lower side effects."/>
COMPOSITION COMPRISING CATECHOLAMINE DERIVATIVES INCLUDING L-2-AMINO-2,3,3-TRIDEUTERO-3-(3,4-DIHYDROXYPHENYL) AND L-2-AMINO-2,3-DIDEUTERO-3-(3,4-DIHYDROXYPHENYL) OR PHYSIOLOGICALLY ACCEPTABLE SALTS THEREOF AND USE OF THE COMPOSITION FOR TREATING PARKINSON'S DISEASE, RESTLESS LEG SYNDROME, AMYOTROPHIC LATERAL SCLEROSIS AND MULTIPLE SYSTEM ATROPHY
首页>
外国专利>
COMPOSITION COMPRISING CATECHOLAMINE DERIVATIVES INCLUDING L-2-AMINO-2,3,3-TRIDEUTERO-3-(3,4-DIHYDROXYPHENYL) AND L-2-AMINO-2,3-DIDEUTERO-3-(3,4-DIHYDROXYPHENYL) OR PHYSIOLOGICALLY ACCEPTABLE SALTS THEREOF AND USE OF THE COMPOSITION FOR TREATING PARKINSON'S DISEASE, RESTLESS LEG SYNDROME, AMYOTROPHIC LATERAL SCLEROSIS AND MULTIPLE SYSTEM ATROPHY
COMPOSITION COMPRISING CATECHOLAMINE DERIVATIVES INCLUDING L-2-AMINO-2,3,3-TRIDEUTERO-3-(3,4-DIHYDROXYPHENYL) AND L-2-AMINO-2,3-DIDEUTERO-3-(3,4-DIHYDROXYPHENYL) OR PHYSIOLOGICALLY ACCEPTABLE SALTS THEREOF AND USE OF THE COMPOSITION FOR TREATING PARKINSON'S DISEASE, RESTLESS LEG SYNDROME, AMYOTROPHIC LATERAL SCLEROSIS AND MULTIPLE SYSTEM ATROPHY
Claimed is a pharmaceutical composition comprising a compound of the Formula (II); ;Described are deuterated catecholamine derivatives prepared by mixing compounds of the general Formula (II) wherein R4 is hydrogen, deuterium, C1-C6alkyl or C5-C6cycloalkyl, deuterated C1-C6alkyl or deuterated C5-C6cycloalkyl. The compounds can easily be prepared by mixing deuterated and non-deuterated compounds in a predefined ratio. The compounds show anti-Parkinson effect at lower doses and show lower side effects.
展开▼
