HBED BISPHOSPHONATE, THEIR CONJUGATES WITH RADIOMETAL AND THEIR USE AS MEDICAL TREATMENT DIAGNOSTIC AGENTS

摘要

The invention relates to compounds of formula I or formula II, which are potential bone imaging agents and therapeutic agents for the treatment of bone tumors and metastases. Some compounds labeled with Ga exhibit excellent bone absorption and retention. The present invention also relates to pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a compound of formula I or formula II, or a pharmaceutically acceptable salt thereof.