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METHODS AND COMPOSITIONS FOR THE TREATMENT OF STATES ASSOCIATED WITH ANOMATIC INFLAMMATORY RESPONSES

机译:治疗与非炎症性反应相关的状态的方法和组合物

摘要

The present invention relates to chemical compounds (for example, a compound exhibiting activity as a mitochondrial uncoupler, or its pharmaceutically acceptable salt and / or hydrate and / or cocrystal; for example, a compound such as niclosamide or its pharmaceutically acceptable salt and / or hydrate and / or cocrystal; for example, a compound such as a niclosamide analog, or a pharmaceutically acceptable salt and / or hydrate and / or cocrystal thereof) that are used, for example, to treat one or more symptoms diseases characterized by abnormal inflammatory response (e.g., inflammatory bowel disease) in a subject (e.g., human). The present description also relates to compositions, as well as other methods for their use and preparation.
机译:本发明涉及化合物(例如,作为线粒体解偶联剂表现出活性的化合物,或其药学上可接受的盐和/或水合物和/或共晶体;例如化合物,如尼克洛沙胺或其药学上可接受的盐和/或水合物和/或共晶体;例如,化合物,例如尼克洛沙胺类似物,或其药学上可接受的盐和/或水合物和/或共晶体,用于治疗一种或多种以异常炎症为特征的症状疾病受试者(例如人)的反应(例如炎性肠病)。本说明书还涉及组合物以及其使用和制备的其他方法。

著录项

  • 公开/公告号EA201890618A1

    专利类型

  • 公开/公告日2018-10-31

    原文格式PDF

  • 申请/专利权人 ФЕРСТ ВЭЙВ БАЙО ИНК.;

    申请/专利号EA20180090618

  • 发明设计人 ГАРИ Д.;ЛУИДЖИ;

    申请日2016-09-01

  • 分类号A61K38;A61K38/16;A61K38/17;

  • 国家 EA

  • 入库时间 2022-08-21 12:52:42

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