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Anti BCMA antibodies, molecules of bisexual pathogens with BCMA and CD3 and their uses

机译:抗BCMA抗体,具有BCMA和CD3的双性病原体分子及其用途

摘要

The present invention provides antibodies that are immune to BCMA. In addition, the related polynucleic acid which can encode the specific BCMA antibody or the binding part of the provided antigen, the cell which represents the antibody or the binding part of the provided antigen, and the related carrier and the antibody or the binding part of the antigen are also introduced. To mark in a detectable manner In addition, the method of using the antibody provided is also introduced. For example, the antibodies provided can be used to diagnose, treat or monitor progress,Cancer regression or stability expressed in BCMA; determining whether patients should be treated for cancer; or determining whether patients have cancer expressed in BCMA, so whether it is possible to use BCMA specific antibody therapy agents for treatment, Multi purpose antibodies against BCMA and CD3 as described in this note.
机译:本发明提供了对BCMA免疫的抗体。另外,可以编码特定的BCMA抗体或所提供的抗原的结合部分的相关多核酸,代表抗体或所提供的抗原的结合部分的细胞,以及相关的载体和抗体或其所结合的部分。抗原也被引入。以可检测的方式进行标记此外,还介绍了使用提供的抗体的方法。例如,所提供的抗体可用于诊断,治疗或监测进展,BCMA中表达的癌症消退或稳定性;确定患者是否应该接受癌症治疗;或确定患者是否患有BCMA中表达的癌症,因此是否有可能使用BCMA特异性抗体治疗剂进行治疗,如本说明中所述针对BCMA和CD3的多用途抗体。

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