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Benzamide Derivative as Histone Deacetylase Inhibitor with Potent Differentiation and Anti-Proliferation Activity

机译:苯甲酰胺衍生物作为组蛋白脱乙酰基酶抑制剂,具有强大的分化和抗增殖活性

摘要

The present invention is related to the preparation and pharmaceutical use of novel benzamide derivatives as defined in the specification of formula (I) as histone deacetylase inhibitors (HDACI), their preparations and the methods of using these compounds or their pharmaceutically acceptable salt in the treatment of cell proliferative diseases, e.g. cancer and psoriasis.
机译:本发明涉及作为组蛋白脱乙酰酶抑制剂(HDACI)的式(I)说明书中定义的新型苯甲酰胺衍生物的制备和药物用途,其制备以及在治疗中使用这些化合物或其药学上可接受的盐的方法细胞增殖性疾病,例如癌症和牛皮癣。

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