Compositions and methods to inhibit stem cell and progenitor cell binding to lymphoid tissue and for regenerating germinal centers in lymphatic tissues

摘要

The present invention relates to dexamethasone for use in a method of reducing stem cell accumulation in the spleen in a human individual, the method comprising administering dexamethasone to the individual prior to stem cell treatment, and wherein the total dose of dexamethasone administered is equivalent to or greater than a dose of 2-3 mg in an adult male 129S1/SvmJ mouse.