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Use of alemtuzumab for the preparation of a medicament for use as a second line therapy for the treatment of multiple sclerosis (ms)
Use of alemtuzumab for the preparation of a medicament for use as a second line therapy for the treatment of multiple sclerosis (ms)
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机译:阿来珠单抗在制备药物中的用途,该药物用作治疗多发性硬化症的二线治疗(ms)
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摘要
A method for treatment of multiple sclerosis (MS) with Campath-1H with significant efficacy and a favourable safety profile is described, which offers an acceptable benefit/risk ratio. Especially described is the use of Campath-1H (alemtuzumab) for the production of a medicament for the treatment of multiple sclerosis (MS), comprising a first treatment cycle followed by at least one further treatment cycle of Campath-1H (alemtuzumab), in which each treatment cycle comprises 1-5 daily doses which are applied on consecutive days, wherein the daily dose is 0 and ‰¤ 12 mg, and wherein each treatment cycle is separated from the next cycle by at least 1 - 24 months. Also described are treatment regimens comprising the administration of less than 12 mg/day of Campath-1H for a period of 1-5 consecutive days.
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