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2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activities
2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activities
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机译:2-氨基嘧啶-6-酮和类似物具有抗癌和抗增殖活性
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摘要
Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.
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