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Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect
Injectable botulinum toxin formulations and methods of use thereof having long duration of therapeutic or cosmetic effect
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机译:具有长的治疗或美容效果的可注射的肉毒毒素制剂及其使用方法
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摘要
This invention provides novel injectable compositions comprising botulinum toxin that may be administered to a subject for various therapeutic, aesthetic and/or cosmetic purposes. The injectable compositions embraced by the invention exhibit one or more advantages over conventional botulinum toxin formulations, including reduced antigenicity, a reduced tendency to undergo unwanted localized diffusion following injection, increased duration of clinical efficacy or enhanced potency relative, faster onset of clinical efficacy, and/or improved stability. According to the invention, single treatment of the compositions by injection affords significant clinical responses and at least a 6-month duration of effect in a subject undergoing treatment, as provided by the described treatment methods.
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