FORMULATION OF ORAL MEDICATED JELLY OF PALANOSETRON HYDROCHLORIDE

摘要

The present study is conducted with the aim to formulated the unit moulded medicated jelly containing Palonosetron hydrochloride for treatment of chemotherapy and radiation therapy induce nausea and vomiting. Jellies are semisolid to thick viscous fluids which is easily taken by patients of advanced age, patients with disability in ingestion of food and drink, in other words, those having difficulty in mastication and swallowing. Moreover the oral medicated jelly formulation with appropriate solidity and slipperiness for swallowing and with good texture which is suitable for improvement of patient compliance. The jelly dosage form can be swallowed easily without water and are soft and smooth.