A PROCESS FOR THE PREPARATION OF DACLATASVIR DIHYDROCHLORIDE

摘要

The present invention provides a process for the preparation of Daclatasvir dihydrochloride by using novel lH-benzotriazole activated MOC-L-Valine intermediate compound of structural formula IV. The present invention further provides the process for removal of Daclatasvir mono impurity compound of structural formula VII from Daclatasvir free base compound of structural formula II.