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LEPTIN COMPOSITIONS AND METHODS FOR TREATING PROGRESSIVE COGNITIVE FUNCTION DISORDERS RESULTING FROM ACCUMULATION OF NEUROFIBRILLARY TANGLES AND AMLYOID BETA
LEPTIN COMPOSITIONS AND METHODS FOR TREATING PROGRESSIVE COGNITIVE FUNCTION DISORDERS RESULTING FROM ACCUMULATION OF NEUROFIBRILLARY TANGLES AND AMLYOID BETA
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机译:瘦素组合物和方法治疗累积的神经原纤维缠结和类脂蛋白引起的渐进性认知功能障碍
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摘要
pThe present disclosure provides compositions containing a leptin product and methods of clinical therapy and diagnostic methods for progressive cognitive disorders. According to one aspect, the described invention provides a method for treating a progressive cognitive disorder. According to another aspect, the described invention provides a method for improving resilience of cognitive function in a subject in need thereof. According to another aspect, the described invention provides a method for identifying an effective therapeutic agent for treating a progressive cognitive dysfunction disease or disorder that results from at least one of accumulation of Aβ, hyperphosphorylation of tau, or accumulation of neurofibrillary tangles./p [US2010113358A1]
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机译:本公开提供了包含瘦蛋白产物的组合物以及用于进行性认知障碍的临床治疗方法和诊断方法。根据一个方面,所描述的发明提供了一种用于治疗进行性认知障碍的方法。根据另一方面,所描述的发明提供了一种用于在需要其的受试者中改善认知功能的复原力的方法。根据另一方面,所描述的发明提供了一种用于鉴定用于进行性进行性认知功能障碍疾病或障碍的有效治疗剂的方法,该疾病或障碍是由Aβ积累,tau过度磷酸化或神经原纤维缠结的积累中的至少一种引起的。 p > [US2010113358A1]
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