SECRETED AND PLASMA MEMBRANE ASSOCIATED BIOMARKERS FOR THE DIAGNOSIS OF HIGHER- AND LOWER-GRADE ASTROCYTOMA

摘要

Disclosed is a method of diagnosing the presence of higher grade astrocytoma /glioblastoma (GBM) or lower-grade astrocytoma (DA or AA) in a human subject using secreted or plasma membrane associated biomarkers, which involves the detection of the expression levels of said genes, alone or in combination, in either tumor tissue samples or body fluids and a diagnostic kit thereof. WO2009122444A2