IN VITRO DIAGNOSTIC METHOD FOR ALZHEIMER'S DISEASE BASED ON THE ALBUMIN REDOX LEVEL IN THE CEREBROSPINAL FLUID.

摘要

In vitro diagnostic method for Alzheimer's disease, based on the albumin redox level in the cerebrospinal fluid. The present invention relates to an in vitro diagnostic method for diagnosing Alzheimer's disease (AD), comprising the steps of: a) determining the content of mercaptoalbumin (HMA) in a sample of cerebrospinal fluid (CSF); and b) comparing the content determined with the content of HMA in CSF in healthy subjects. If the HMA content is less than that of the healthy subjects, it is indicative of AD. In an embodiment, the HMA level is also determined in blood or plasma and a difference or ratio is calculated.