In various embodiments, a compensato can be attachable to an anvil (22760) of a fastening instrument. The compensator can comprise a support layer (24226) configured to be attached to the anvil and a scaffold (24222) attached to the support layer. In at least one embodiment, the scaffold can comprise a plurality of scaffold layers (24227) comprised of a biocompatible material and a plurality of cavities, wherein the layers and the cavities can define a matrix favorable to tissue and cellular ingrowth.
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