Method that utilizes mass spectrometry MALDI-TOF and iPLEX for detection of bar code genetic variants and its application

摘要

the object of the application is a way using mass spectrometry maldi-tof and iplex detection variants of genetic bar coding.in addition, the notification contains also apply this method to detecting variants of genetic bar coding introduced to cells or tissues or organisms and / or tracking selected populacjand cells in time and / or the offspring of single cells and to study clonal evolution during the process of malignancy and / or tracking of cells during the processes of differentiation and organogenesisaru00f3wno in vitro and in vivo.