Crystalline form of the complex of dihydrate triaquabis(1,3-dimethylxanthine)copper(II) and method for producing it

摘要

the application relates to crystalline forms of complex triakwabis dihydrate (1.3 - dimetyloksantyno) copper (ii) with formula 1, applicable as a component of free release and a controlled concentration of theophylline.the application also covers the method of manufacturing crystalline forms of complex triakwabis dihydrate (1.3 - dimetyloksantyno) copper (ii) with formula 1, which is characterized by the fact that one part of the molar acetate hydrated copper (ii)soluble in water and subjected to the reaction with two parts molowymi aqueous solution 1.3-dimetyloksantyny 80% with the addition of concentrated acetic acid.after a minimum of 14 days is a crystalline form of triakwabis dihydrate (1.3-dimetyloksantyno) copper (ii) of formula 1.