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INTRATHECAL ADMINISTRATION OF MTOR INHIBITORS FOR THE THERAPY OF NEURODEGENERATIVE, NEUROINFLAMMATORY AND NEUROONCOLOGIC DISEASES
INTRATHECAL ADMINISTRATION OF MTOR INHIBITORS FOR THE THERAPY OF NEURODEGENERATIVE, NEUROINFLAMMATORY AND NEUROONCOLOGIC DISEASES
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机译:鞘内施用MTOR抑制剂治疗神经退行性疾病,神经炎性疾病和神经痛性疾病
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摘要
The invention relates to the use of inhibitors of the enzyme mTOR kinase (mammalian target of rapamycin) in the treatment of neuro-oncologic diseases, in particular tuberous sclerosis, neurodegenerative diseases, in particular Alzheimer's disease, and neuroinflammatory diseases, in particular multiple sclerosis and primary progressive aphasia, via intrathecal, or preferably intraventricular, administration of said inhibitors.
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