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CELL LINES FOR PRODUCING RECOMBINANT GLYCOPROTEINS WITH DI-ANTENNARY N-GLYCANS, METHODS USING THE SAME, AND RECOMBINANT GLYCOPROTEINS
CELL LINES FOR PRODUCING RECOMBINANT GLYCOPROTEINS WITH DI-ANTENNARY N-GLYCANS, METHODS USING THE SAME, AND RECOMBINANT GLYCOPROTEINS
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机译:用双腺嘌呤N-聚糖生产重组糖蛋白的细胞系,使用其的方法和重组糖蛋白
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摘要
The present invention relates to a genetically modified cell line with reduced expression of GnTIVa/b and/or GnTV, a method for the production of glycoproteins having N-glycans with a reduced number of tri- and/or tetra-antennary N-glcyans using said cell line, and respective glycoproteins.
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