Use of ICAM-1 for the prevention or treatment of neurological diseases

摘要

A pharmaceutical composition for use in the prevention or treatment of a neurological disease, comprising an ICAM-1 protein (intercellular adhesion molecule 1), or a fragment or a variant thereof, as an active ingredient, in which the Neurological disease is a disease selected from the group consisting of Alzheimer's disease, epilepsy, and mild cognitive impairment, and is caused by at least one selected from the group consisting of the formation of beta-amyloid plaque in neurons, the reduction of neprilysin expression in neurons and a combination thereof.