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Compounds, compositions and corresponding uses, for the prevention and / or treatment of dyslipidemias
Compounds, compositions and corresponding uses, for the prevention and / or treatment of dyslipidemias
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机译:用于预防和/或治疗血脂异常的化合物,组合物和相应用途
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摘要
Compound comprising a polar head, comprising at least one hydroxyl residue, on which a single unsaturated fatty acid comprising between 16 and 24 carbon atoms and having 1 to 6 unsaturations in cis configuration is used for use in preventing and / or treating, in a subject, a hypoxia lipointoxication associated with the excess presence in the biological membranes of non-adipocyte cells, fatty acids, in particular saturated long chain fatty acids and / or sterols; said compound being chosen from manide monooleate, 3-hydroxy-2,2-bis (hydroxymethyl) propyl oleate, N, Ndiethanoleamide and mixtures thereof; said lipointoxication being associated by hypoxia in said subject to a pulmonary pathology.
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