ML - IAP PEPTIDES INDUCE ANTI-MELANOMA CYTOTOXIC T-CELL RESPONSE

摘要

The present invention relates to polypeptide fragments capable of raising aspecific T-cell response, wherein said fragment comprises a peptide consistingof at least 9 consecutive amino acid residues of ML-IAP as well as to saidfragments for use as medicaments. The invention furthermore relates to use ofsaid polypeptide frag-ments in the manufacture of a medicament for treatmentof a clinical condition, such as cancer. The invention also relates to methodsof selecting a peptide comprising a fragment of ML-IAP for use in a vaccinecomposition as well as to vaccine composi-tions comprising isolated ML-IAP(SEQ ID NO:1) and/or one or more fragments thereof.