METHODS FOR GENERATING IMMUNE RESPONSE USING CATIONIC-LIPOSOME-MEDIATED NUCLEIC ACID DELIVERY

摘要

The present invention is in the fields of drug delivery, and specifically,cationic liposome-based vaccines. In embodiments,this invention provides methods of making ligand-targeted (e.g., antibody-orantibody fragment-targeted) liposomes usefulfor the delivery of molecules to induce immune responses against viralantigens or to treat or prevent viral diseases. The specificityof the delivery system is derived from the targeting ligands.