THE USE OF TWO MICRORNAS IN LUNG CANCER PROGNOSIS AND DRUG PREPARATION

摘要

The present invention relates to use of two microRNAs in detection of lungcancer prognosis and in medicine preparation. Particularly, the inventionrelates to acomposition comprising two small RNA molecules microRNA-150 andmicroRNA-886-3p, a device comprising the composition used in detection of lungcancer prognosis and in preparation of medicaments for inhibiting mammal andhuman lung cancer metastasis. Specifically, the expression levels of microRNA-150and microRNA-886-3p can be used as the prognostic criteria of lung cancerprognosis,wherein high expression level of the gene combination indicates favorabletherapeuticeffect. The invention also relates to a device detecting the expression levelsofmicroRNA-150 and microRNA-886-3p in mammalian and human lung cancer and amethod for detecting the expression levels of microRNA-150 and microRNA-886-3pin samples.