首页>
外国专利>
ETANERCEPT FOR USE IN THE TREATMENT OF CHRONIC BRAIN INJURY
ETANERCEPT FOR USE IN THE TREATMENT OF CHRONIC BRAIN INJURY
展开▼
机译:用于治疗慢性脑损伤的止痛药
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method of using biologics to treat chronic brain injury or spasticity due to stroke, trauma and other causes. Preferred embodiments include perispinal, parenteral, transepidermal or intranasal use of TNF antagonists. The TNF antagonists include TNF receptor fusion proteins, TNF monoclonal antibodies (mAbs), humanized TNF mAbs, fully human TNF mAbs, chimeric TNF mAbs, domain TNF antibodies, mAB fragments, anti-TNF nanobodies, dominant negative TNF constructs and TNF inhibitory single chain antibody fragments. One of the preferred embodiments of this invention is the perispinal administration of etanercept for treatment of mammals following stroke. The use of Trendelenburg positioning, catheters, pumps, or depot formulations are included.
展开▼