BISTABLE GENETIC TOGGLE SWITCH COMPRISING A PAIR OF RECIPROCAL REPRESSORS AND A POSITIVE FEEDBACK LOOP BASED ON DNA-BINDING PROTEINS

摘要

The present invention refers to a bistable genetic toggle switch with a pair of mutual repressors and a positive feedback loop with a pair of activators which are based on DNA- binding proteins, such that one of the repressor and activator pairs binds each of the two predefined binding sites for DNA-binding proteins.