A difference image generation method includes: a step for, on the basis of a first whole image and a second whole image obtained after the first image, generating a first difference image which sets the area where the first and second whole images do not differ as a mask area; and a step for generating a second difference image by setting the area other than the mask area of the first difference image as a section corresponding to the second whole image, and setting the mask area of the first difference image as transparent color information.
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