MICROFLUIDIC-BASED MULTIPLEX CELL ASSAY FOR DRUG COMPOUND TESTING

摘要

The invention in some aspects relates to high throughput methods and devices for evaluating mechanical and morphological properties of cells, such as blood cells under conditions of cell attachment and regulated gas conditions. In some aspects, the invention relates to methods for assessing cell adhesion under regulated conditions, for example gas concentration, temperature, shear force, and attachment to proteins. In some aspects, the invention relates to methods and devices for identifying therapeutic agents. In some aspects, the invention relates to methods and devices for diagnosing and/or characterizing a condition or disease in a subject, for example, by measuring a property of a cell from the subject under controlled conditions.