BIFONAZOLE PHARMACEUTICAL COMPOSITION AND LIVER-PROTECTING EFFECT THEREOF

摘要

Disclosed are a bifonazole pharmaceutical composition and a liver-protecting effect thereof. The bifonazole pharmaceutical composition contains bifonazole and a natural product compound (I) separated from dried fritillaria thunbergii bulbs and having a novel structure. The bifonazole and the compound (I) increase the GSH content in mouse liver tissue, decrease the MDA content, inhibit TG accumulation, and have a certain liver-protecting effect. When used together, the bifonazole and the compound (I) have a better treatment effect, may be developed into a liver-protecting drug, and have prominent substantive features and represent notable progress with respect to the prior art.