首页>
外国专利>
Recombinant poxviral vectors expressing both rabies and OX40 proteins, and vaccines made therefrom
Recombinant poxviral vectors expressing both rabies and OX40 proteins, and vaccines made therefrom
展开▼
机译:同时表达狂犬病和OX40蛋白的重组痘病毒载体及其疫苗
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides vectors that contain and co-express in vivo or in vitro immunogenic polypeptides or antigens together with an OX40L polypeptide, which functions as a genetic adjuvant. Together, the immunogenic polypeptide and the OX40L polypeptide elicit an immune response in animal or human, which is greater than the immune response elicited by the immunogenic polypeptide alone. In a particular example, the invention provides vectors encoding a Rabies G immunogenic polypeptide and a canine OX40L genetic adjuvant, which vectors elicit strong immune responses in canine against rabies virus
展开▼