COMBINATION THERAPIES FOR ERADICATING FLAVIVIRUS INFECTIONS IN SUBJECTS

摘要

Compositions that specifically cleave target sequences in Flavivirus, for example Zika virus include a Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) associated endonuclease, a guide RNA sequence complementary to a target sequence in a Zika virus and an anti- viral agent. These compositions are administered to a subject for treating an infection or at risk for contracting a Zika virus infection.