首页> 外国专利> METHOD FOR THE IMMUNOLOGICAL DIAGNOSIS OF A SAMPLE WITH A POTENTIAL INFECTION WITH AN ARBOVIRUS AND TEST KITS SUITABLE FOR THIS PURPOSE

METHOD FOR THE IMMUNOLOGICAL DIAGNOSIS OF A SAMPLE WITH A POTENTIAL INFECTION WITH AN ARBOVIRUS AND TEST KITS SUITABLE FOR THIS PURPOSE

机译:适于目的的带有虫媒和测试盒的样本的免疫学诊断方法

摘要

The present invention relates to a method for the immunological diagnosis of a sample from a patient with a potential infection with an arbovirus, wherein a) a sample is brought into contact with a plurality of antigens provided such that they are separated from one another on a solid phase, at least the following antigens being used: aa) the "non-structural protein 1" of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, bb) an "envelope protein" of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, cc) an "envelope protein" of a second arbovirus or an immunologically reactive part thereof having at least 8 amino acids, dd) the "non-structural protein 1" of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids and ee) an "envelope protein" of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids, b) the solid phase is washed to separate non-specific bindings, c) the immune complex formed on the solid phase is converted into a signal and d) the test method is evaluated by comparing the relative signal strengths.
机译:本发明涉及一种用于免疫诊断来自虫媒病毒潜在感染的患者的样品的方法,其中a)使样品与多种抗原接触,所述多种抗原被提供为使得它们彼此分离。固相,至少使用以下抗原:aa)第一虫媒病毒的“非结构蛋白1”或其具有至少8个氨基酸的免疫反应部分,bb)第一虫媒病毒的“包膜蛋白”或具有至少8个氨基酸的免疫反应部分,cc)具有第二种虫媒病毒的“包膜蛋白”或其具有至少8个氨基酸的免疫反应部分,dd)具有第三种虫媒病毒的“非结构蛋白1”或其具有至少8个氨基酸的免疫反应部分,并且ee)第三虫媒病毒的“包膜蛋白”或其具有至少8个氨基酸的免疫反应部分,b)将固相洗涤至单独的非特异性结合,c)固相上形成的免疫复合物转化为信号,d)通过比较相对信号强度评估测试方法。

著录项

  • 公开/公告号WO2018073208A1

    专利类型

  • 公开/公告日2018-04-26

    原文格式PDF

  • 申请/专利权人 MIKROGEN GMBH;

    申请/专利号WO2017EP76411

  • 申请日2017-10-17

  • 分类号G01N33/569;

  • 国家 WO

  • 入库时间 2022-08-21 12:44:26

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