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KIT FOR PREPARING DISEASE-TREATING AGENT, DISEASE-TREATING AGENT AND METHOD FOR PREPARING DISEASE-TREATING AGENT

机译:用于准备疾病治疗剂的试剂盒,疾病治疗剂和用于制备疾病治疗剂的方法

摘要

The present invention addresses the problem of providing a disease-treating agent which exerts an excellent effect in treating diseases requiring an emergency surgery such as heart failure and which is efficacious at a certain level for a large number of patients. The present invention pertains to a kit for preparing a disease-treating agent, said kit comprising a) a fibrinogen solution, b) a thrombin solution and c) mesenchymal stem cells, in separate forms respectively. It is preferred that the mesenchymal stem cells c) are allogeneic to a subject to be treated. Also, the present invention pertains to a kit for preparing a disease-treating agent, said kit being to be used by, before using, suspending the mesenchymal stem cells c) in either the fibrinogen solution a) or the thrombin solution b), and then spraying the cell suspension thus obtained directly to a disease site substantially simultaneously with the thrombin solution b) or fibrinogen solution a) that is not used in the suspending step.
机译:本发明解决了提供一种疾病治疗剂的问题,该疾病治疗剂在治疗需要紧急手术的疾病如心力衰竭中发挥优异的效果并且在一定程度上对大量患者有效。本发明涉及用于制备疾病治疗剂的试剂盒,所述试剂盒包含分别以单独形式的a)纤维蛋白原溶液,b)凝血酶溶液和c)间充质干细胞。间充质干细胞c)优选与待治疗的受试者同种异体。另外,本发明涉及用于制备疾病治疗剂的试剂盒,所述试剂盒通过在使用之前将间充质干细胞c)悬浮在纤维蛋白原溶液a)或凝血酶溶液b)中来使用,和然后与悬浮步骤中未使用的凝血酶溶液b)或纤维蛋白原溶液a)同时直接将如此获得的细胞悬浮液直接喷洒到疾病部位。

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