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KIT FOR PREPARING DISEASE-TREATING AGENT, DISEASE-TREATING AGENT AND METHOD FOR PREPARING DISEASE-TREATING AGENT

机译:用于准备疾病治疗剂的试剂盒,疾病治疗剂和用于制备疾病治疗剂的方法

摘要

The present invention addresses the problem of providing a disease-treating agent which exerts an excellent effect in treating diseases requiring an emergency surgery such as heart failure and which is efficacious at a certain level for a large number of patients. The present invention pertains to a kit for preparing a disease-treating agent, said kit comprising a) a fibrinogen solution, b) a thrombin solution and c) mesenchymal stem cells, in separate forms respectively. It is preferred that c) the mesenchymal stem cells are allogeneic to a subject to be treated. Also, the present invention pertains to a kit for preparing a disease-treating agent, said kit being to be used by, when in use, suspending c) the mesenchymal stem cells in either a) the fibrinogen solution or b) the thrombin solution, and then spraying the cell suspension thus obtained directly to a disease site substantially simultaneously with either b) the thrombin solution or a) the fibrinogen solution that is not used in the suspending step.
机译:本发明解决了提供一种疾病治疗剂的问题,该疾病治疗剂在治疗需要紧急手术的疾病如心力衰竭中发挥优异的效果并且在一定程度上对大量患者有效。本发明涉及用于制备疾病治疗剂的试剂盒,所述试剂盒包含分别以单独形式的a)纤维蛋白原溶液,b)凝血酶溶液和c)间充质干细胞。优选c)间充质干细胞对待治疗的受试者是同种异体的。另外,本发明涉及一种用于制备疾病治疗剂的试剂盒,所述试剂盒通过在使用时将c)间充质干细胞悬浮在a)纤维蛋白原溶液或b)凝血酶溶液中来使用,然后基本上与b)凝血酶溶液或a)在悬浮步骤中未使用的纤维蛋白原溶液同时地直接将如此获得的细胞悬液喷雾到疾病部位。

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