COMPOSITION FOR PROMOTING STEM CELL ACTIVITY, COMPRISING HISTONE DEACETYLASE INHIBITOR AND PRIMING FACTOR AS ACTIVE INGREDIENTS

摘要

The present invention relates to a composition for promoting stem cell activity, comprising a histone deacetylase inhibitor and a priming factor as active ingredients. When stem cells were treated with a low-concentration histone deacetylase inhibitor and priming factor, the activity of the stem cells significantly improved. In particular, primed MSCs promote a cell movement, colony-forming activity, and anti-inflammatory capability in terms of cell culturing conditions and thereby improve hypertension, inflammatory disease, or immune disease treatment effects and thus are expected to become a useful treatment strategy.