首页> 外国专利> METHOD FOR SELECTING INDIVIDUALS TO BE ADMINISTERED IMMUNE CHECKPOINT INHIBITOR

METHOD FOR SELECTING INDIVIDUALS TO BE ADMINISTERED IMMUNE CHECKPOINT INHIBITOR

机译:选择要管理的免疫检查点抑制剂的个人的方法

摘要

[Problem] To provide a method for selecting individuals for whom administration of an immune checkpoint inhibitor would be effective, by extracting tumor tissue from individuals who have developed tumors and determining the level of expression of B7-H3 in the extracted tumor tissue. [Solution] A method for selecting individuals to be administered an immune checkpoint inhibitor when treating a tumor, said selection method characterized by comprising: (1) a step for extracting tumor tissue from said individuals; (2) a step for determining the degree of expression of B7-H3 in the tumor tissue extracted at (1); and (3) a step for selecting, as subjects to be administered an immune checkpoint inhibitor, individuals for whom it has been determined that the level of expression of B7-H3 is negative.
机译:[问题]提供一种通过从已发生肿瘤的个体中提取肿瘤组织并确定所提取的肿瘤组织中B7-H3的表达水平来选择对其施用免疫检查点抑制剂有效的个体的方法。 [解决方案]一种在治疗肿瘤时选择要给予免疫检查点抑制剂的个体的方法,所述选择方法的特征在于包括:(1)从所述个体中提取肿瘤组织的步骤;以及(2)确定在(1)中提取的肿瘤组织中B7-H3的表达程度的步骤; (3)选择被确定为B7-H3的表达水平为阴性的个体作为接受免疫检查点抑制剂的对象的步骤。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号