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ANG-(1-7) AND DERIVATIVE OLIGOPEPTIDES FOR THE TREATMENT OF TRAUMATIC BRAIN INJURY AND OTHER COGNITIVE IMPAIRMENTS
ANG-(1-7) AND DERIVATIVE OLIGOPEPTIDES FOR THE TREATMENT OF TRAUMATIC BRAIN INJURY AND OTHER COGNITIVE IMPAIRMENTS
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机译:ANG-(1-7)和衍生性寡肽治疗创伤性脑损伤和其他认知障碍
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摘要
The present invention provides oligopeptides, in particular, Ang-(1-7) derivatives, and methods for using and producing the same. In one particular embodiment, oligopeptides of the invention have higher blood-brain barrier penetration and/or in vivo half-life compared to the native Ang-(1-7), thereby allowing oligopeptides of the invention to be used in a wide variety of clinical applications including in treatment of cognitive dysfunction and/or traumatic brain injury.
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