PREDICTIVE METHODS OF ASCENDING AORTA DILATION AND BICUSPID AORTIC VALVE

摘要

The present invention relates to methods for diagnosing ascending aorta dilation or bicuspid aortic valve, determining the probability of suffering from ascending aorta dilation, predicting the progression of ascending aorta dilation and kits useful for carrying on said methods. The methods employ the level of the specific circulating miRNA molecules, miR-718, miR-130a, miR-122 and miR-486 for the diagnosis and reagents for detecting the specific miRNA in the kits.