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A METHOD OF MANUFACTURING A SUSPENSION OF NANOPARTICLES OF TADALAFIL OR SILDENAFIL CITRATE
A METHOD OF MANUFACTURING A SUSPENSION OF NANOPARTICLES OF TADALAFIL OR SILDENAFIL CITRATE
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机译:一种制备他达拉非或西地那非柠檬酸盐的纳米颗粒悬浮液的方法
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摘要
A method of manufacturing a suspension of nanoparticles of tadalafil or sildenafil citrate consisting in that, a solution of tadalafil or sildenafil citrate in dimethyl sulfoxide (DMSO) is prepared, and an aqueous solution of a least one dispersing agent is prepared, then under continuous homogenization a solution of tadalafil or sildenafil citrate is added portion- wise to the aqueous solution of at least one dispersing agent, afterwards homogenization is continued until a suspension of tadalafil or sildenafil citrate nanoparticles is obtained.
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