首页>
外国专利>
NANOPARTICULATE MATERIALS AND METHODS FOR TARGETING IRON ACQUISITION AND METABOLISM FOR TREATING BACTERIAL INFECTIONS
NANOPARTICULATE MATERIALS AND METHODS FOR TARGETING IRON ACQUISITION AND METABOLISM FOR TREATING BACTERIAL INFECTIONS
展开▼
机译:用于治疗细菌感染的针对铁的获取和代谢的纳米微粒材料和方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
Novel biocompatible nanoparticles preferably based on a calcium or gallium analogue of Prussian blue, or independently an analogue of magnesium, or aluminum were designed and synthesized to take advantage of their ability to penetrate the bacterial cell membrane of the invading pathogen in an animal such as a human in both Gram-positive bacteria (e.g. Staphylococcus aureus) and Gram-negative bacteria (e.g. Pseudomonas aeruginosa), and undergo selective ion exchange with intracellular iron to disrupt iron metabolism in such pathogenic bacteria for antibacterial applications.
展开▼