METHOD FOR PREPARING CANCER STEMNESS CELL LINE THROUGH METABOLIC STRESS, AND CANCER CELL PREPARED THROUGH SAME

摘要

The present invention relates to a cancer cell line having stemness, and a method for preparing the same, more particularly, to inducing a cancer cell into a stemness cancer cell by applying metabolic stress to the cancer cell, and even more particularly, to preparing and establishing a cancer stemness cell line through repeated culturing in a glucose-deficient culture medium. The main characteristics of the cancer stemness cell line prepared by the method are high resistance to apoptosis in glucose-deficient environment and high resistance to anticancer agents.