MULTIMERIC INHIBITORS OF BACTERIAL TYPE III SECRETION SYSTEM

摘要

Organic compounds showing the ability to inhibit effector toxin secretion or translocation mediated by bacterial type III secretion systems (T3SS) are disclosed. The disclosed type III secretion system inhibitor compounds are useful for combating infections by Gram-negative bacteria such as Pseudomonas aeruginosa and other bacteria having such type III secretion systems.