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The composition for detecting mutations of epidermal growth factor receptor geneEGFR and the EGFR mutation kit consisting of the compounds

机译:用于检测表皮生长因子受体基因EGFR突变的组合物和由该化合物组成的EGFR突变试剂盒

摘要

The present invention relates to a composition for detecting an epidermal cell growth factor receptor gene mutation and to a kit comprising the composition and, more specifically, to a primer and probe set composition for detecting an epidermal cell growth factor gene mutation, and to a kit for detecting an EGFR gene mutation, comprising the composition. The method according to the present invention can not only predict and diagnose responsiveness to a therapeutic agent for the prognosis of a cancer patient, but also predict a cancer metastasis or relapse. Thus, the method can be useful for the purposes of determining the need to administer an anticancer therapeutic agent and guiding the direction of future treatment, and for monitoring a cancer metastasis or relapse.
机译:本发明涉及用于检测表皮细胞生长因子受体基因突变的组合物和试剂盒,更具体地说,涉及用于检测表皮细胞生长因子基因突变的引物和探针组组合物,以及试剂盒用于检测EGFR基因突变的方法,其包含所述组合物。根据本发明的方法不仅可以预测和诊断对用于癌症患者的预后的治疗剂的响应性,而且可以预测癌症的转移或复发。因此,该方法可用于确定需要施用抗癌治疗剂并指导未来治疗的方向,以及用于监测癌症转移或复发的目的。

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