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PCL PCL patch scaffold for tissue regeneration and preparing method thereof

机译:用于组织再生的pcl PCl贴片支架及其制备方法

摘要

The present invention relates to a poly caprolactone (PCL) patch tissue regenerating support and a preparing method thereof. More specifically, the PCL patch tissue regenerating support preparing method includes the steps of: adding the PCL and an acid to an organic solvent and stirring the mixture to prepare a solution; preparing an electrospinning solution by adding a growth factor to the solution and stirring the solution; and supplying the prepared electrospinning solution to a syringe pump and driving an electrospinning solution to collect the nanofibers arranged in a fusing shape in a collector. According to the present invention, the PCL patch tissue regenerating support can be used to the treat chronic perforation of the eardrum and ensure a high eardrum recovery rate while reducing the cost and dependency of the treatment including surgeries therefor. The PCL patch tissue regenerating support can also be used for the treatment and regeneration of other damaged tissues, simulate the tissue structure of other human body parts, and be used for the development and application of various tissue regeneration supports.
机译:本发明涉及一种聚己内酯贴片组织再生载体及其制备方法。更具体地,PCL贴片组织再生支持物的制备方法包括以下步骤:将PCL和酸加入到有机溶剂中,并搅拌混合物以制备溶液。通过向溶液中添加生长因子并搅拌溶液来制备静电纺丝溶液;将制备的静电纺丝溶液供应至注射泵,并驱动静电纺丝溶液以将呈融合形状排列的纳米纤维收集在收集器中。根据本发明,PCL贴片组织再生支持物可用于治疗鼓膜的慢性穿孔并确保高的鼓膜恢复率,同时降低成本和包括手术的治疗依赖性。 PCL贴片组织再生载体还可以用于其他受损组织的治疗和再生,模拟人体其他部位的组织结构,并且可以用于各种组织再生载体的开发和应用。

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