siRNA siRNA - Polymeric siRNA-Glycol Chitosan Nanocomplex for Tumor-targeted Delivery of siRNA and Method for Preparing the Same

摘要

The invention for tumor targeting delivery of siRNA, siRNA oligomer for inhibiting the expression of particular genes in tumor cells relates to a glycol chitosan nanocomposite and a manufacturing method thereof. siRNA oligomer for tumor targeting the delivery of a siRNA according to the invention - glycol chitosan nanocomposites may have enhanced siRNA transfer function with respect to tumor cells and effectively inhibit the expression of a target gene by an siRNA delivery.