2 22 TTREATMENT OF TUMOR NECROSIS FACTOR RECEPTOR 2 TNFR2 RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO TNFR2

摘要

The present invention relates to antisense oligonucleotides that specifically target the expression and / or function of tumor necrosis factor receptor 2 (TNFR2), particularly antisense oligonucleotides targeted to natural antisense polynucleotides of tumor necrosis factor receptor 2 (TNFR2). The invention also relates to the identification of such antisense oligonucleotides and to the use thereof for the treatment of diseases and disorders associated with the expression of TNFR2.