Potential autoantibody biomarkers for the detection and diagnosis of dementia

摘要

The present invention relates to an autoantibody biomarker for dementia diagnosis and a dementia diagnosis kit including the same. More particularly, the present invention relates to an autoantibody biomarker selectively recognizing ATCAY (ataxia, cerebellar, cayman type), NME7 (NME/NM23 family member 7) and NOL3 (nucleolar protein 3) which are unusually increased in blood of a dementia patient than a normal person so as to be capable of dementia diagnosis, and a diagnosis kit for diagnosing dementia including an antigen recognizing the same. The kit for diagnosing dementia including autoantibodies of ATCAY, NME7 and NOL3, which can be used as the marker for dementia diagnosis of the present invention, can be used for early diagnosis of dementia by using blood of a patient to diagnose dementia very easily.