首页> 外国专利> METHOD FOR PRODUCING NANOLIPOSOME PARTICLES CONTAINING PEPTIDES CAPABLE OF EASILY PERMEATING TO SKIN

METHOD FOR PRODUCING NANOLIPOSOME PARTICLES CONTAINING PEPTIDES CAPABLE OF EASILY PERMEATING TO SKIN

机译:包含能够容易渗透皮肤的肽的纳米脂质体颗粒的制备方法

摘要

Provided is a method for producing nanoliposome particles of stabilized peptides, comprising the following steps: adding, to alcohol, lecithin, cholesterol, ceramide, sodium stearoyl lactate, polysorbate-80, stearic acid, butylated hydroxytoluene, and tocopheryl acetate, and then uniformly wetting the same; adding silk peptide, potassium hydroxide, and a remaining amount of purified water, and heating and mixing the mixture to 60 to 80°C; and passing the solution through a high-pressure homogenizer at a pressure of 600 to 1000 bar for 2 to 4 times, and then cooling the same thereafter.;COPYRIGHT KIPO 2018
机译:提供了一种稳定肽的纳米脂质体颗粒的制备方法,其包括以下步骤:向醇,卵磷脂,胆固醇,神经酰胺,硬脂酰乳酸钠,聚山梨酯-80,硬脂酸,丁基化羟基甲苯和生育酚乙酸酯中添加,然后均匀润湿相同;加入丝肽,氢氧化钾和剩余量的纯净水,并将混合物加热并混合至60至80℃;将溶液通过高压均质器在600至1000 bar的压力下进行2-4次,然后将其冷却。; COPYRIGHT KIPO 2018

著录项

  • 公开/公告号KR20180032479A

    专利类型

  • 公开/公告日2018-03-30

    原文格式PDF

  • 申请/专利权人 AGRICULTURE CORPORATE SOON;

    申请/专利号KR20160121769

  • 发明设计人 BYUN KYEONG BONGKR;

    申请日2016-09-22

  • 分类号A61K8/14;A61K8/34;A61K8/55;A61K8/64;A61K8/68;A61Q19/00;

  • 国家 KR

  • 入库时间 2022-08-21 12:40:25

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