MANUFACTURING METHOD OF ANIMAL MODEL OF TRACHEAL STENOSIS AND ANIMAL MODEL MANUFACTURED THEREBY

摘要

The present invention relates to a method for producing a trachea stenosed animal model, and a trachea stenosed animal model produced thereby. To this end, the method comprises the following steps: intubating a tube in the trachea in an animal other than human; leaving the animal to cause damage to the tracheal mucosa; and removing the tube from the animal′s trachea and leaving the animal to cause tracheal stenosis. The tracheal stenosis is caused in a pathway similar as tracheal stenosis takes place is caused in vivo, and the animal model can provide a basis for various studies such as pathophysiology, early detection methods, prevention, and treatment associated with tracheal stenosis.